Nature

Predicting RNA 3D structure and conformers using a pre-trained secondary structure model and structure-aware attention

Determining RNA three-dimensional (3D) structure and conformers remains a grand challenge in structural biology, primarily owing to the scarcity of experimental data, the intrinsic flexibility of RNA ...
Nature

Quality assessment of RNA 3D structure models using deep learning and intermediate 2D maps

RNA (ribonucleic acid) plays an essential role in gene expression regulation and numerous cellular processes. Its biological function largely depends on its three-dimensional (3D) structure. Unlike ...
Phys.org

Mitochondrial enzyme's atomic-level structure reveals how it processes RNA

Researchers at the Department of Cell and Molecular Biology, Karolinska Institutet have captured the first detailed molecular snapshots of human polynucleotide phosphorylase (hPNPase) in action, ...
EurekAlert!

Study shows how to identify drugs altering RNA structure and function

On the left are three forms of the same RNA molecule, which is stabilised into a single form (on the right) by mitoxantrone. Ribonucleic acids (RNAs) serve as messengers between DNA and protein ...