Phenotypic drug discovery (PDD) involves using a living system to identify compounds that alter the phenotype of a given disease. PDD has evolved from screening a few compounds in animals to testing ...

Cell migration is a key cellular process that drives major developmental programs. To mimic and mechanistically understand cell migration in these different contexts, different assays have been ...

This article explores the causes of high-throughput screening assay failures, how these failures manifest in screening ...

SPT Labtech, a global leader in innovative laboratory automation, today announced a strategic collaboration with Semarion, a University of Cambridge spin-out company from the Cavendish Laboratory ...

Single-cell analysis is a ubiquitous laboratory technique that allows researchers to probe the myriad biomolecular states of cells. Single-cell assays can reveal gene and protein expression patterns, ...

Apoptosis, or programmed cell death, is a tightly regulated biological process necessary for normal tissue maintenance and development. However, aberrations in apoptotic signaling networks are ...

Quality by design is critical for cell and gene therapy manufacturing where process controls directly influence product ...