Human protein kinases constitute a large superfamily of about 500 genes, historically classified into subfamilies based on phylogenetic relationship. However, many kinases remain unclassified.

In structural bioinformatics, the efficiency of predicting protein similarity, function, and evolutionary relationships is crucial. Our approach proposed herein leverages protein energy profiles ...

A team of researchers say that the current computational methods for predicting how proteins will bind are inadequate. They ...

Installed in a custom Titan Krios, the laser phase plate enhances motion correction, early‑frame recovery, and 3D classification and alignment.