Accurate RNA splicing is essential for gene expression and human health, yet predicting how DNA sequence variations affect ...

Researchers at The University of Texas MD Anderson Cancer Center have performed a comprehensive evaluation of five artificial intelligence (AI) models trained on genomic sequences, known as DNA ...

An international research team led by Forschungszentrum Jülich and the IPK Leibniz Institute has developed an artificial intelligence model that predicts where regulatory proteins dock onto plant DNA ...

The DNA foundation model Evo 2 has been published in the journal Nature. Trained on the DNA of over 100,000 species across the entire tree of life, Evo 2 can identify patterns in gene sequences across ...

A joint research team has developed an automated design technology that enables the creation of DNA origami structures that ...

The thermodynamics of DNA secondary structure formation is fundamental to understanding diverse biological processes, such as DNA replication 1 and repair 2. It also underlies many biotechnological ...

*Important notice: bioRxiv publishes preliminary scientific reports that are not peer-reviewed and, therefore, should not be regarded as conclusive, guide clinical practice/health-related behavior, or ...

Genome annotation models play a pivotal role in modern biological research, providing the tools necessary to identify genes, their exon–intron structure and other functional elements directly from DNA ...

In a recent study published in the journal Nature, researchers at the Arc Institute describe the development and advantages of “Evo 2”. Evo 2 is a novel biological foundation model trained on a ...

R-loops are structures that form when a strand of RNA (red) forms a stable structure with double-stranded DNA, causing one strand of the DNA to form a loop. R-loops are associated with gene ...