Completing DNA replication triggers genomic instability in bacteria

If you are anything like us, whenever you plan a journey, you spend a remarkable amount of time thinking about the start and ...
News Medical

BioEcho launches EchoLUTION™ FFPE DNA Kit for a simplified DNA extraction from FFPE samples

BioEcho Life Sciences, the biotechnology company delivering rapid and sustainable nucleic acid extraction products, announces the EchoLUTION FFPE DNA Kit release, for an innovative way to extract DNA ...
Nature

Telomere-to-telomere DNA replication timing profiling using single-molecule sequencing with Nanotiming

Current temporal studies of DNA replication are either low-resolution or require complex cell synchronisation and/or sorting procedures. Here we introduce Nanotiming, a single-molecule, nanopore ...
Nature

Transcription and DNA replication collisions lead to large tandem duplications and expose targetable therapeutic vulnerabilities in cancer

In the present study, we used a total of 6,193 whole-genome-sequenced tumors to perform a detailed analysis of somatic SVs. We revealed that large TDs result from TRCs and that tumor cells with ...