If you are anything like us, whenever you plan a journey, you spend a remarkable amount of time thinking about the start and ...

Cells have evolved careful checks to ensure DNA is copied only once, but how they switch on replication at the right moment ...

A new discovery by researchers at the RIKEN Center for Biosystems Dynamics (BDR) in Japan upends decades of assumptions regarding DNA replication. Led by Ichiro Hiratani and colleagues, the ...

Replication Protein A (RPA) plays a pivotal role in DNA replication by coating and protecting exposed single-stranded DNA, and acting as a molecular hub that recruits additional replication factors.

PARP inhibitors (PARPi), known for their ability to induce replication gaps and accelerate replication forks, have become potent agents in anticancer therapy. However, the molecular mechanism ...

The Polymerase Chain Reaction (PCR) is a technique for the amplification of DNA in vitro (this describes experiments with cells outside their normal environment). PCR amplifies DNA using complementary ...

New findings suggest the end-replication problem, an old standby of biology textbooks, is twice as intricate as once thought. Half a century ago, scientists Jim Watson and Alexey Olovnikov ...

DNA replication is the process by which a cell makes an identical copy of its DNA. This process is performed at the beginning of every cell division so that when the cell divides, each daughter cell ...

Scientists uncovered DNA's double helix structure in 1953. James Watson and Francis Crick proposed the model. It explained ...

Scientists have discovered that a gene normally considered a DNA-protecting "good guy" can become dangerous when cells make too much of it. The gene, EXO1, acts like molecular scissors that help ...

In our bodies, there are trillions of cells. From white blood cells to skin cells, each type has its own specific function which helps us perform tasks and survive. But what makes up these cells and ...