Nature

Polygenic Risk and Exposure Severity Predict Trajectories of PTSD: A Prospective Cohort Study

Posttraumatic stress disorder (PTSD) is persistent over time, thus identifying risk factors for chronic PTSD is crucial for clinical research. Trauma exposure severity and polygenic liability are two ...
Nature

Distribution and elimination kinetics of midazolam and metabolites after post-resuscitation care: a prospective observational study

Sedatives are frequently administered to mitigate undesirable physiological responses and alleviate discomfort during post-resuscitation care, including temperature control. Despite the numerous ...
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Prospective observational study of nutritional and immunological indices as predictive biomarkers of response to immune checkpoint inhibitors in non-small cell lung cancer (ICI ...

The efficacy and safety of furmonertinib in patients with advanced EGFR-mutated NSCLC and leptomeningeal metastases. This is an ASCO Meeting Abstract from the 2024 ASCO Annual Meeting I. This abstract ...
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Prospective observational study investigating the impact of treatment sequence using regorafenib and FTD/TPI for metastatic colorectal cancer on overall survival (OSERO study).

Real-world analysis of irinotecan (iri) with or without fluorouracil (5FU) in the second line treatment (2L) of metastatic colorectal cancer (mCRC). DKN-01 plus bevacizumab and chemotherapy as ...