Definition: The extracellular matrix is the non-cellular network of proteins and polysaccharides that surrounds cells, gives tissues mechanical structure, and provides biochemical and mechanical ...

Laminins are heterotrimeric glycoproteins that form a fundamental scaffold within the extracellular matrix, particularly in basement membranes. Each laminin molecule comprises α, β and γ chains ...

To investigate whether the cortical structural abnormalities observed in cases of lissencephalic pathologies are linked to mechanical abnormalities, we performed rheological tests on cortical ...

Rhobo6, a light microscopy probe, gives scientists an unprecedented look at the extracellular matrix -- the collection of organized molecular structures that fills the spaces between cells in our ...

A groundbreaking study led by Children's Hospital Los Angeles has found a novel mechanism behind neuroblastoma progression: the shape and structure of the extracellular matrix. The study, led by ...

A new study led by Children's Hospital Los Angeles has found a novel mechanism behind neuroblastoma progression: the shape and structure of the extracellular matrix. In addition, the team developed an ...

Before arriving at Janelia three years ago, Postdoctoral Scientist Antonio Fiore was designing and building optical instruments like microscopes and spectrometers. Fiore, a physicist by training, came ...

Researchers in Taiwan have developed a cell-free extracellular matrix material from axolotl skin that helped mouse burn ...

Fascia of live mouse pancreas, in which the extracellular matrix is labeled with Rhobo6 (red) and nuclei are labeled with Hoechst (cyan). Maximum intensity projection shown. Before arriving at Janelia ...