Promoters are DNA sequences that initiate transcription and regulate gene expression in organisms 1. The TATA box is a common promoter sequence in many eukaryotic genes, recognized by transcription ...

DNA methylation (DNAm) is a key epigenetic mark that shows profound alterations in cancer. Read-level methylomes enable more in-depth analyses, due to their broad genomic coverage and preservation of ...

Work has begun on something once-unthinkable: creating human DNA from scratch. Artificial DNA has long been an ethical minefield, with fears of a generation of ‘designer babies’ with pick ‘n’ mix ...

With GROVER, a new large language model trained on human DNA, researchers could now attempt to decode the complex information hidden in our genome. GROVER treats human DNA as a text, learning its ...

DNA synthesis is vital to several processes in biopharmaceutical innovation, including the development of gene therapies, CRISPR gene editing, antisense oligonucleotides and RNA therapies. The need ...