To map the mammalian brain and its various functions with increasing precision, neuroscientists rely on high-resolution imaging techniques and other advanced experimental tools. These now include high ...

By applying machine-learning models to single-cell brain recordings taken from humans in conversation, a research team ...

Neurons, the uber-connected nerve cells that act as a main switchboard for the brain, are central to some incredibly complicated processes. They make it possible to think, walk, speak, and breathe.

Different neuronal cells have a diverse range of activity patterns, but the cause has remained unclear. In mice, maps of brain-wide inputs to individual neurons that do or do not show activity ...

Primary sensory neurons convert external stimuli into electrical signals, yet how heterogeneous neurons encode distinct sensations remains unclear. In vivo dorsal root ganglia (DRG) imaging with ...

A study in zebrafish shows that neuronal microexons regulate brain activity by modulating cAMP signaling. Loss of these ...

Pediatricians and parents — and, really, anyone who works with children — have long known that a child’s social needs evolve with age. Yale researchers have now discovered the neurological signaling ...

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease with no cure and limited treatment options. One of the earliest signs of ALS is overactive brain signals known as ...

The altered presence of tiny fragments of neuronal genes, called microexons, causes hyperarousal in zebrafish. This is the ...

Researchers discover that disrupted neuronal microexons cause a permanent spike in cAMP signaling, driving severe hyperarousal, insomnia, and hyperactivity.