A protein that appears in postsynaptic protein agglomerations has been found to be crucial to their formation. The Kobe University discovery identifies a new key player for synaptic function and sheds ...

Endogenous cannabinoids, also known as endocannabinoids, are neurotransmitters (i.e., chemical messengers naturally produced by the body) that transmit specific signals from one neuron to another.

A research group led by Specially appointed professor, Dr. Tatsuo Suzuki of Shinshu University School of Medicine developed a new purification protocol for Postsynaptic density (PSD) lattice, a core ...

Long-term depression (LTD) between cortical layer 4 spiny stellate cells and layer 2/3 pyramidal cells requires the activation of NMDA receptors (NMDARs). In young rodents, this form of LTD has been ...

Functional synapse formation requires tight coordination between pre- and post-synaptic termini. Previous studies have shown that postsynaptic expression of heparan sulfate proteoglycan syndecan-2 ...

Synaptic plasticity describes the biological process that enables learning and memory through facilitating changes in the connections between synapses. Interaction with the external world results in ...