This study aims to use a static-based solubility method for measuring the solubility of lumiracoxib at a temperature of 308–338 K and pressure of 120–400 bar for the first time. The obtained ...

Accurate prediction of thermodynamic solubility by machine learning remains a challenge. Recent models often display good performances, but their reliability may be deceiving when used prospectively.

Research conducted at the State University of Campinas (UNICAMP) in São Paulo state, Brazil, shows that heat treatment of pea protein and addition of guarana extract result in a compound with ...

A large share of medicines developed today may never reach patients for a surprisingly simple reason: they cannot dissolve well enough in water. For most treatments, the oral route remains the gold ...

New data for an existing equation allow accurate estimates of the solubilities of many petrochemicals in water. Correlation results for estimating water solubility are presented for a wide variety of ...

These plots show powder X-ray diffraction measurements of three different types of formulations: simple mixing (a, d), the conventional evaporation/condensation ...

Scientists studying how nanomaterials behave in the environment have developed a new technique for assessing how quickly the tiny particles dissolve in aqueous solutions (Environ. Sci. Technol., DOI: ...

Poor drug solubility has become a challenge for pharmaceutical companies, with an approximation of 40% of drugs in their developing stages demonstrating problems with drug solubility. Additionally, ...