Bioengineers at Queen Mary University of London have taken a significant step forward in the development of laboratory-based models of human tissues that may be used as alternatives to animal testing.

Innovative three-dimensional (3D) systems have become a focus of research due to their ability to better mimic cell-cell and cell-extracellular matrix interactions. Current advances in 3D modelling ...

The potential of tissue engineering to deliver clinical advances hinges on a connected ecosystem that includes academics, funding agencies, entrepreneurs, investors, the pharmaceutical industry and ...

In this Innovation Spotlight, Treutlein shares her excitement of using organoids to model the human brain, harnessing AI to accelerate laboratory discoveries, and discusses how massive-scale ...

For the 300,000 Americans living with the immune disease scleroderma, better treatments can't come soon enough. The rare and sometimes fatal illness stiffens and scars tissue in organs like the lungs, ...

In a bid to gain further understanding of the etiology and pathogenesis of metabolic dysfunction–associated steatohepatitis (MASH), a team of researchers has created 3D bioprinted liver models. MASH, ...

Microscopic images of human tissue are a cornerstone of biomedical research and clinical diagnostics. Yet despite their importance, these images often remain difficult to analyze systematically and to ...

A research team at the RIKEN Center for Biosystems Dynamics Research (BDR) in Japan report they have created a model of the blood-brain barrier using modularized tissue derived from human cells. The ...

For the first time, scientists have grown functional, brain-like tissue without using any animal-derived materials or added biological coatings. The development opens the door to more controlled and ...

Commonly, it involves a computer-assisted motorized device that deposits biocompatible materials, viable cells, growth factors, proteins, nucleic acids, drugs, and supporting components in a ...

Animal models are established, important tools for preclinical safety and efficacy testing. Companies are advancing more “humanized” models to better reflect human responses, while at the same time ...

Lab-grown skin captures the complexities of real disease to develop more effective treatments for scleroderma and other life-threatening conditions. For the 300,000 Americans living with the immune ...