A vaccine developed more than a century ago to fight tuberculosis may offer a surprising new benefit, helping treat Type 1 diabetes. Dr. Denise Faustman of Massachusetts General Hospital says the BCG ...

A live-attenuated tuberculosis (TB) vaccine candidate in development elicits a much more balanced and effective immune response compared to the existing vaccine used across much of the world, ...

In the course of investigating the use of Bacillus Calmette-Guérin for high-risk individuals who have type 1 diabetes (T1D), researchers hoped—and found—that BCG could substantially reduce the chance ...

This diagram illustrates the timeline and current status of various TB vaccine candidates in clinical trials, highlighting the diversity of vaccine types and their potential impact on TB prevention ...

Tuberculosis remains a leading cause of infectious mortality worldwide, driven by the airborne transmission of Mycobacterium tuberculosis and the emergence of drug-resistant strains. The only licensed ...

Tuberculosis dates back more than 9,000 years. It is the most infectious bacterial disease and in 2022 10.6 million people fell ill with it. Of these 23% occurred in Africa. The only vaccine against ...

There is no highly effective vaccine against tuberculosis (TB), which remains an infection of global concern. Charles Kyriakos Vorkas, MD, an infectious diseases physician-scientist at the Renaissance ...

In a paper published in the Journal of Clinical Investigation, a research team at Johns Hopkins Medicine and the Johns Hopkins Bloomberg School of Public Health reports developing a therapeutic ...

It has been several years since a new tuberculosis (TB) drug advanced into Phase III trials, but momentum in the field is now picking up, with a vaccine and two novel treatments progressing through ...

Mycobacterium tuberculosis (Public Health Image Library, NIAID, Image ID: 18139) Mycobacterium tuberculosis (Public Health Image Library, NIAID, Image ID: 18139) Tuberculosis (TB) is the number one ...

CAMBRIDGE, MA -- A large-scale screen of tuberculosis proteins has revealed several possible antigens that could be developed as a new vaccine for TB, the world’s deadliest infectious disease. In the ...