Nearly 100 years ago, a seemingly simple discovery revolutionized the microscope. The introduction of phase contrast, which ...

The scanning electron microscope (SEM) delivers high resolution, high depth of field, and an image quality as if microscopic objects are seen by the naked eye. This makes it not only a powerful ...

How large, fully folded proteins can pass through cell membranes without destroying them has long been one of the open questions in cell biology. Using cryo-electron microscopy (cryo-EM), Leonid ...

Cryo-electron microscopy (cryo-EM) can help scientists determine the three-dimensional structure of proteins in unprecedented detail. Jacques Dubochet, former group leader at EMBL, shared the 2017 ...

Stretching protein samples in all directions pulls molecules farther apart, allowing them to be visualized using only light ...

Fifteen years ago, physicists worked out a method to increase image contrast by hitting the electron imaging beam with an ...

In a basement lab in Brandeis' Rosenstiel building, a refrigerator-sized microscope dominates a small, windowless room. On its surface, it looks like a featureless white box. Yet inside, it's a study ...

Electron microscopy is a powerful technique that provides high-resolution images by focusing a beam of electrons to reveal fine structural details in biological and material specimens. 2 Because ...

They can image a wide range of materials and biological samples with high magnification, resolution, and depth of field, thereby revealing surface structure and chemical composition. Industries like ...

Traditional electron microscopy techniques include scanning electron microscopy (SEM) and transmission electron microscopy (TEM), where electrons that interact with the sample are imaged. 4 The ...

If you want to build semiconductors at home, it seems like the best place to start might be to find a used scanning electron microscope on eBay. At least that’s how [Peter Bosch] kicked off his ...