In the case of SARS-COV-2, vROs are composed of double-membrane vesicles (DMVs) that originate upon remodelling of the membranes of the endoplasmic reticulum (ER) (Fig. 1). The biogenesis of the vROs ...

Flaviviruses strategically utilize the endoplasmic reticulum (ER) in their replication cycles. However, the role of ER autophagy (ER-phagy) in viral replication process remains poorly understood. Here ...

The rate of HIV infection continues to climb globally. Around 40 million people live with HIV-1, the most common HIV strain. While symptoms can now be better managed with lifelong treatment, there is ...

Researchers at Umeå University have identified two human cell proteins, NUP98 and NUP153, that play a crucial role in how viruses such as tick-borne encephalitis virus (TBEV), West Nile virus, and ...

Chinese scientists uncover how the Nipah virus hijacks a host protein (NSUN2) to boost its replication through a dual mechanism, simultaneously stabilizing viral RNA and modifying a key viral protein, ...

According to an article published in the journal PLOS Pathogens, severe COVID-19 patients can be divided into two distinct groups: those with a high viral load and relatively little inflammation, and ...

Zika virus hijacks a key protein implicated in brain development for its own replication. Researchers led by Associate Professor Priya Shah at the University of California, Davis (CA, USA), have ...

Learn how viral vector release testing for AAV and lentiviral vectors utilizes orthogonal assays for titer, capsid content, ...

Mitochondrial deoxyribonucleic acid (mtDNA) is essential for cellular energy production and overall cell function. Abnormalities in mtDNA are linked to various diseases and are also implicated in ...