Nature

These ‘master’ proteins protect us from deadly mutations — and could inspire new drugs

Biology has clever ways to mask the effects of potentially harmful gene mutations. Scientists are investigating how this ...
The Lancet

Advances in understanding the impact of sex on kidney health and disease

Biological differences exist between males and females in kidney structure and function, leading to sex heterogeneity in the presentation and outcomes of chronic kidney disease (CKD) and response to ...
RMD Open

Elevated plasma monounsaturated fatty acids and their associations with disease activity, adiposity and sex in patients with rheumatoid arthritis: a cross-sectional study

Background Rheumatoid arthritis (RA) is a chronic autoimmune disease associated with systemic inflammation and metabolic ...
Nature

Defining the Environmental Adaptations of Genus Devosia: Insights into its Expansive Short Peptide Transport System and Positively Selected Genes

The ureC is the largest of the genes encoding urease functional subunits and is essential for a functional urease 70, 71. The strain DS-56 was isolated from the island soil near sea where urea acts as ...
C&EN

Design and Synthesis of 2-(4-Bromophenyl)Quinoline-4-Carbohydrazide Derivatives via Molecular Hybridization as Novel Microbial DNA-Gyrase Inhibitors

Department of Chemistry, College of Science, King Faisal University, Al-Ahsa 31982, Saudi Arabia Department of Chemistry, Faculty of Science, Sohag University, Sohag 82524, Egypt ...